Ingredients In Skin Care Products
There are many skincare techniques that individuals can use to manage wrinkles, lines, sagging skin, and other imperfections and signs of aging. These may include laser techniques, dermabrasion, chemical peels, and creams containing retinol, peptides, stem cells, and other ingredients discovered within the past twenty years. Recently, however, science and research have played an even more important role in the development of anti-aging skincare products.
As new technologies become available, skincare researchers explore how to take advantage of those innovations in the dermatological sector. With new gene expression discoveries and other innovations, the field of anti-aging techniques has made huge leaps in giving people the ability to enhance their appearances, enabling them to look and feel years younger, and teaching them how to prevent and successfully treat skin disorders or imperfections.
Without these scientific advances and the research performed to prove the effectiveness and safety of these new methods, important anti-aging skincare products and procedures may never have come to light. Skincare research is constantly evolving, and results are shared with other professionals through scientific publications like the Journal of Dermatology. These scientists also present their experimental findings at conferences organized by prestigious institutions like The American Academy of Dermatology.
The science involved in developing anti-aging skincare products and techniques, particularly those related to DNA, stem cells, liposomes, and nanotechnology, is fascinating and a sign of how far we have advanced in the field of skincare. In the past, only laser treatments, retinol creams, or other, more aggressive treatments were effective for skin disorders such as severe sun damage. Now, new advances in stem cell research have produced a number of skincare and anti-aging products in the forms of lotions, creams, serums, and sunscreens that contain stem cell repair ingredients.
Anti-oxidants can help with the loss of collagen and are quicker and longer lasting when combined with increasingly new and effective technology, such as liposomes and nanotechnology. Peptides can also boost collagen production. When used in conjunction with new ingredient delivery systems, these substances work much more effectively since they can now penetrate the skin‘s outer dermal layer, affect the skin‘s cells, and produce new collagen.
Consumers are more educated today than ever before, and they know if they are being scammed. This new breed of consumer looks to companies that perform diligent research and conduct safe, clinical trials for information. Consumers don‘t want products that might cause harm to people, animals, or the environment during the course of research, development, or production. Fortunately, the new science of skincare is making the grade. Consumer satisfaction is sure to grow when people explore what is available from a scientific point of view. These products deliver on their promises to restore damaged skin and to minimize or eliminate the signs of aging.
The public‘s continued interest in and commitment to health and wellness education and concern for beauty will be instrumental in generating more research, more innovative development, and newer products for skin protection.
Ingredients In Skin Care Products
The DNA in your Skin
Research and testing have allowed scientists to discover single nucleotide polymorphisms in our skin that helps us to evaluate overall skin health. Working with this technology, companies now have a host of DNA skincare products that specifically address aging, wrinkling, and damage caused by the sun and environmental hazards. DNA skincare products are constantly being researched, and new developments are continuously implemented.
These products are tested for UV protection capabilities, and for their ability to protect skin under all kinds of environmental assaults. They are tested for quality, purity, effectiveness, and performance. These products are formulated based on leading research from around the globe, and using information about mitochondria DNA and molecular skin structure.
DNA products can be created for individual clients in special spa-type salons or clinics after a skin test is performed. The skin test involves taking a cell sample from inside the mouth and sending it away for analysis. A highly trained technician or physician will then make recommendations for skincare products based on the individual‘s DNA results. Other DNA-based skincare products can be purchased with just a general assessment of your skin‘s state of health (e.g., anti-wrinkling for women over 40). DNA specific skincare products can be generically made for wrinkles, anti-aging, rejuvenation of dull skin, and to address specific areas.
Wilma Schumann‘s DNA Plus is an excellent example of a product for consumers looking for the best skincare available. Products like this use science and technology to create skincare lines for cleansing, moisturizing, acne care, anti-aging, anti-wrinkling, toning, and fine tuning the pigment of the skin, face, lips, and eyes.
Fetal Cells in Skincare
Scientific research conducted by physicians and scientists in various laboratories around the world has proved that there are healing properties in fetal cells for restoring and slowing the aging process of the skin. Cell banks have been established to provide fetal cells from scrapings, so there is a nearly endless supply available for research and the development of skincare products.
Through years of research, physicians have discovered that fetal skin cells have the unique ability to heal wounds without scarring. Switzerland created a biotechnology process to extract the rich proteins responsible for scar-less wound healing from cultured fetal skin cells. The products developed by Neocutis, including PSP, are the newest, most cutting-edge cosmaceuticals in the marketplace.
Note: The technology using fetal skin cells is still very controversial in the skincare industry.
The term nanotechnology refers to the ability to handle matter that is very small in scale—about the size of molecules or atoms. The new and innovative materials being developed with nanotechnology have a wide spectrum of applications; for instance, nanotechnology is utilized in medicine to produce energy, electronics, and biomaterials. In essence, any technique or tool that is small enough can be referred to as nanotechnology. Having the control and the ability to change matter on the scale of nanometers permits scientists to build working systems that are remarkably light, strong, intelligent, and durable.
Speaking at the 68th annual meeting of the American Academy of Dermatology, Adnan Nasir (MD, PhD, and FAAD), the clinical assistant professor in the Department of Dermatology at the University of North Carolina, presented an overview of nanotechnology and how nanoparticles may eventually be used in cosmetic products.
According to Dr. Nasir, ―Research in the area of nanotechnology has increased significantly over the years, and I think there will be considerable growth in this area in the near future. The challenge is that there is no standard at this time to evaluate the safety and efficacy of topical products that contain nanosized particles.
With the aid of nanotechnology, skincare products can better penetrate beneath the skin‘s surface, allowing them to target specific areas. Skincare products that use nanotechnology to convert ingredients into nanosized elements improve the blood‘s circulation and in the process reduce dark circles under the eyes by eliminating the waste products and oxidized particles that cause the dark circles in the first place. Nanotechnology can also be used for other pigmentation issues. Combining vitamin K with nanotechnology alleviates the appearance of unsightly spider veins. While vitamin K has been used to treat spider veins in the past, it can only sufficiently penetrate the skin for a good effect through the use of nanotechnology.
People that want the wrinkles and lines removed from their lips no longer have to undergo lip augmentation. Through nanotechnology, the fullness of the lips can be increased with lipstick containing plumper ingredients. Stretch marks, scars, and sagging skin can also be helped with nanotechnology.
The microscopic particles used in nanotechnological skincare treatments can penetrate the skin—absorption is quick. Skincare products, such as anti-aging creams and sunscreen, can now be manufactured as nano skincare products to increase their effectiveness. The primary benefit of using nanoparticles in sunscreens is that the particles can enter all the tiny pits and cracks of the skin, giving protection that is more evenly distributed on the skin‘s surface. Sunscreen products that use nanoparticles are more cosmetically appealing because they seem to vanish into the skin when applied. This leads people to use them more frequently and consistently, contributing to the positive anti-aging effects attributed to the product.
Sunscreens using macro-sized particles actually absorb ultraviolet light and can be toxic to human, whereas sunscreens containing nanoparticles prevent ultraviolet absorption. Products that use nanotechnology are considered natural products. The products do not simply coat the skin‘s surface; they penetrate–an advancement that has been a long time coming.
Liposomes are structures composed of phospholipids, the same materials found in cell membranes. Phospholipids‘ heads are attracted to water while their tails are repelled by water, creating a bilayer which can be used to artificially build liposomes. The word liposome literally derives from the Greek words fat and body. Liposomes were developed by Dr. Bangham in 1965, to transport drugs, vaccines, and other materials directly to the body site where they were needed. Liposomes can be used in the same way to carry cosmetics to the skin. The first cosmetics containing liposomes were developed in 1986; now they are commonplace in hundreds of gels, creams, and moisturizers.
Using liposomes to deliver cosmetic Ingredients In Skin Care Products increases the penetration and diffusion of the active ingredients and allows the substances to be more selectively transported to the target areas. Release time is also spread out, making the cosmetics last longer. These substances have greater stability and there are few, if any, negative side effects.
When a gel or cream containing liposomes is smoothed on the skin‘s surface, the liposomes merge with cell membranes and release active substances into the target cells. The effectiveness of the liposomes depends on the size used. Generally, the smaller the liposomes, the more deeply they penetrate and the longer the active ingredients last. Liposomes can be added to moisturizers to ensure good hydration. The phospholipids used in the construction of liposomes contain moisture and encourage the ingredients to better adhere to the skin, hydrating it. Liposomes also create a barrier on the skin‘s surface, trapping moisture underneath the lipid‘s membrane. This hydrates the skin‘s layers and repels other substances such as sunlight or sweat.
Some anti-wrinkle creams utilize liposomes in combination with vitamins A and E, avocado, shea butter, or soya. The gels are usually light and soft on the skin and help diminish crow‘s-feet and fine lines. Gels using the liposome delivery system are soothing as they bind in moisture and lubricate skin tissues.
By working with modern genetic information, skincare research has made great strides in the past few decades. A genoma is the ordered set of genetic material that makes up a living organism. Scientists completed the ordering of the human genome in 2003, ushering in the post-genoma era and bringing even more exciting innovations to the skincare industry.
When the genoma sequence for Malassezia globosa (M. globosa) was completed, innovations in dandruff and dry skin conditions began to evolve. M. globosa is a yeast fungus found naturally in living cells that can cause dandruff and other severe dry skin conditions. DNA sequencing technologies have helped scientists learn much more about these conditions than ever before.
Now, with DNA microarrays, researchers working on the production of new skincare products can determine the gene expression of an entire human genome, all at once. Different skincare products can be more accurately compared and assessed by using DNA microarrays. The variations of gene expression produced by a peptide, or any biologically active substance, provide us with new and significant information on the effect a given substance has on skin tissue.
DNA microarray techniques have spurred the invention and production of new products and therapies that can reduce the appearance of fine lines and wrinkles while also improving the tone and clarity of the skin. DNA microarrays are also useful in understanding abnormal scarring. In the future this could help in the repair processes of both normal and abnormal wounds.
Vialox is an anti-wrinkle Ingredients In Skin Care Products that is very potent. It comes in powder form and has been proven to reduce wrinkling—through the contraction of muscle cells—by 49%. It is similar to Botox, but it is a topical cream rather than an injection, making it attractive to people reluctant to try facial injections.
Vialox produces a Botox-like reduction in wrinkles. In clinical studies, volunteers applied Vialox to one half of their faces twice a day for 28 days. The subjects were women between the ages of thirty and sixty. The primary purpose of the study was to determine the effectiveness of Vialox on crow‘s-feet— but it was discovered to be equally effective on other facial wrinkles as well.
Vialox is composed of a pentapeptide (pentapeptide-3) that relaxes muscles in the skin. Pentapeptide-3 is manufactured by a Swiss pharmaceutical company. It works by blocking nerves in the postsynaptic membrane and then binds to specific receptors in the nerve, preventing sodium ions from being released. This stops the electric charge in the nerve (known as depolarization) which would otherwise cause wrinkles. Vialox is very similar to curare, the poison used by some South American tribes for blow darts.
The Vialox powder kit is sold in two vials—one contains penpeptide-3 in powder form, while the second contains a solvent that dissolves the powder. The purpose of the two-vial packaging is to keep the active ingredient fresh for as long as possible.
Only one or two drops of Vialox, smoothed into the face, are needed to address crow‘s-feet, wrinkles on the forehead, frown lines, and nasolabial folds. Results can be seen within a month. The product lasts up to two weeks after mixing. Apply Vialox twice daily for the first month, and then maintain the positive effects with a daily application thereafter. A 14-day supply of Relax Plus Vialox sells for about forty-two dollars.
Revinage is made from a retinoid-like vegetable source that offers extra benefits for the skin. Retinoids are used as skin plumpers as they smooth and reduce wrinkles from inside the skin. They help stimulate collagen production and rejuvenate the skin, adding renewed elasticity. One of most known Ingredients In Skin Care Products .
Natural retinoids are derived from vitamin A, a substance contained in plant materials. They work to unclog pores, increase collagen production, and erase fine lines within just a few weeks‘ time. Synthetic retinoids are very similar to natural retinoids. They activate retinoic acid receptors (RARs) in the skin. This helps trigger plumping, wrinkle smoothing, and lightening of the skin. However, retinoids can sometimes be irritating to the skin. Revinage is formulated to eliminate this type of reaction by targeting only the RARs that are necessary to produce the desired effect. Most synthetic retinoids can be used in direct sunlight, while true retinoids cannot. While using a retinoid, such as Retin-A, you must apply a sunscreen to avoid sunburn or skin damage. (You may want to wear sunscreen even with synthetic retinoids just to ensure that there is no toxicity and that the retinoids remain stable in the sunlight).
Revinage decreases wrinkles and lightens the skin by reducing melanin production. It can also control oil production, resulting in fewer acne breakouts. Revinage also acts as an anti-inflammatory agent with anti-oxidant effects.
PhytoCellTec is a technology developed by Mibelle Biochemistry that protects skin stem cells. It is derived from the stem cells of a Swiss apple tree, which produces apples famous for their longevity which are rich in phytonutrients and suffer little shriveling over time. The plant‘s stem cells are obtained using PhytoCellTec‘s technology and placed Ingredients In Skin Care Products into cosmetic skincare products to guarantee that skin cells live longer with less wrinkling. This technology helps protect human skin cells, slowing the aging process and minimizing wrinkling of the skin. The skin creams made with PhytoCellTec are enhanced through the addition of vitamins C and E.
The actual PhytoCellTec process intentionally damages a tiny piece of the plant material in order to induce calluses. These calluses are incubated on slide plates and, when developed, are harvested in order to obtain stem cells. These stem cells are then processed, captured, and placed into liposomes.
Melanostatin 5 (or nonoapeptide-1) is a synthesized peptide used in cosmetic products to rid the skin of abnormal pigmentation, reduce wrinkles, and smooth the skin‘s surface. Peptides are strings of amino acids, the building blocks of life. When applied to the skin in the form of creams or lotions, synthesized peptides act as messengers to skin cell receptors, telling them how to react.
Melanostatin 5 is a synthesized peptide that works by stopping the melanocyte hormone that is stimulated by UV light. Melanostatin 5 instructs the melanocytes to stop producing melanin. This can lighten the skin‘s pigmentation or prevent hyper-pigmentation. When included in anti-aging products, Melanostatin 5 can also help lighten dark circles under the eyes. The ingredient delivers very positive effects within four to twelve weeks when used in cosmetic creams and lotions. It lightens the skin by at least 33% with the initial application. Over time, and with continued use, that percentage increases.
This is a safe lightening ingredient that is quite effective and reliable. Products containing Melanostatin 5 do take time to work, but once they have taken effect, the results are usually very good. However, it is not a permanent solution to hyper-pigmentation. If a client stops using the cream or lotion, the product ceases to work and results fade.
Products should contain a high percentage of Melanostatin 5 in order to guarantee positive results. A minimum of 2-4% of the cream is the norm. Complimentary ingredients should also be present for the best outcomes. Ingredients such as (5%) Matrixl, (10%) Argireline, (3%) Rigin, (3%) Eyeliss and (5%) Regu-age are excellent additions. When you read the product label, look for higher percentages of each substance to achieve the best results.
With the addition of Melanostatin 5, skincare products lighten age spots, freckles, and melasma.
They work in anti-aging creams to help brighten skin damaged by the sun, even out blotchiness, and firm the skin at the cellular level.
Darkout is useful for people with uneven skin tones, no matter what their ethnicity. When added to face creams, body lotions, hand creams, and anti-aging creams, it cures blotchiness, sun damage, hormonal damage, scarring, and the effects of aging. Skin color changes may be the result of anything from smoking, to genetics, to emotional stress, in addition to the causes mentioned above.
Skin cosmetics containing the ingredient Darkout give the skin a radiant, luminous appearance. It evens skin pigmentation, helps to fade age spots and wrinkles, and helps with hyper-pigmentation (when an area of the skin darkens due to an increase in melanin production). Hyper-pigmentation can occur in the epidermis, the dermis, or occasionally in both areas. An increase in melanin production can be caused by overexposure to the sun, inflammation of the skin tissue, or any other skin damage such as acne scarring. People with darker skin colors are more likely to have hyper-pigmentation issues, particularly if they spend a lot of time in the sun.
There are various types of hyper-pigmentation. Melasma presents as dark brown patches on the face—particularly the forehead, temples and cheeks. It is usually found in pregnant women or women taking birth control pills. About ten percent of the time, it may also be seen in women who are not pregnant or in men. All of these patients, however, have melasma due to sun exposure. Melasma does fade in women, but rarely fades in men.
Lentigines are brown, oval-shaped spots caused by repeated sun exposure. They are also known as liver spots (solar lentigines). Usually found on the face and hands, they begin to appear around middle-age and increase as people get older. Age spots may be associated with melanoma or skin cancer. Some hyper-pigmentations may be due to drug use or disease.
Darkout is a naturally-derived product, made up of African star grass roots called corms. It works by inhibiting tyrosinase, reducing the synthesis of melanin.
Argireline is an ingredient used in some anti-wrinkle cosmetic products. These products are applied directly to the skin. Argireline is actually the trademark name for acetyl hexapeptide-3, a molecule that is part of a peptide chain. Argireline is made up of a chain of six amino acids or proteins and so is shorter than a Botox string.
Argireline helps erase deep creases, wrinkles, and lines around the forehead and the eyes, like those found in crow‘s-feet. When Argireline is added to a chemically-made cosmetic compound, it relaxes the muscles that cause the face to smile, frown, or make other expressions. Its function is very similar to that of Botox. By relaxing tension on the face, lines and wrinkles are much less likely to form in the first place. Neurotransmitters in the brain tell our facial muscles to tense in certain situations; Argireline inhibits these neurotransmitters, allowing the muscles to relax. When this ingredient is combined with other cosmetic components, it makes a wonderful, moisturizing, anti-aging, skin-resurfacing product.
Clinical experiments have shown that creams containing 10% Argireline reduced the depth of wrinkles in 27% of the women tested. Even with lower concentrations of the ingredient (5%), women still saw a 17% reduction in lines and creases.
Axolight is an active ingredient contained in products that lighten the skin. It is a chemical structure composed of ArabinoXylo-Oligosaccharides. It works by inhibiting melanogenesis (a process that causes the cells to produce melanin—the pigment that gives our skin, eyes, and hair their unique colors).
Melanogenesis also causes us to tan when we are out in the sunlight, especially those of us with lighter skin. People with very fair skin may burn when exposed to the sun due to melanogenesis. By including Axolight as an active ingredient in skincare products, melanogenesis is inhibited and causes less damage to the skin. Axolight can specifically inhibit the tyrosinase-related protein enzyme needed to activate tyrosinase—this limits melanogenesis at different levels and reduces skin pigmentation.
Aging, the sun‘s rays, and stress all have negative effects on our skin. Axolight can reduce these effects by preventing age spots and other types of damage. It can lighten skin, and allow the cream you‘ve applied to work longer after sun exposure. It has proven very successful for all-over sun care, including the hands and the face, prior to, during, and after exposure.
In one clinical test, a cream containing 3% Axolight was smoothed on a woman‘s skin every other day. She was then exposed to the sun‘s UV rays daily for ten days. Her results showed that melanogenesis was reduced by 88%.
In other experiments, Axolight was compared with creams containing Arbutin, a skin lightening cream. Of the control group using Axolight cream, 91% of the people showed a lightened effect on their skin, while only 82% of those using Arbutin exhibited a similar lightening effect. Axolight cream worked more quickly than the Arbutin cream.
Cosmetically, Axolight is useful for lightening the skin; when included in anti-aging creams, it addresses age