Top 5 Main Ingredients In Anti Aging Skin Care-Vialox-PhytoCellTec-Matrixyl 3000- Argireline-


Vialox is an anti-wrinkle ingredient that is very potent. It comes in powder form and has been proven to reduce wrinkling—through the contraction of muscle cells—by 49%. It is similar to Botox, but it is a topical cream rather than an injection, making it attractive to people reluctant to try facial injections.

Vialox produces a Botox-like reduction in wrinkles. In clinical studies, volunteers applied Vialox to one half of their faces twice a day for 28 days. The subjects were women between the ages of thirty and sixty. The primary purpose of the study was to determine the effectiveness of Vialox on crow’s-feet— but it was discovered to be equally effective on other facial wrinkles as well.

Vialox is composed of a pentapeptide (pentapeptide-3) that relaxes muscles in the skin. Pentapeptide-3 is manufactured by a Swiss pharmaceutical company. It works by blocking nerves in the postsynaptic membrane and then binds to specific receptors in the nerve, preventing sodium ions from being released. This stops the electric charge in the nerve (known as depolarization) which would otherwise cause wrinkles. Vialox is very similar to curare, the poison used by some South American tribes for blow darts.

The Vialox powder kit is sold in two vials—one contains penpeptide-3 in powder form, while the second contains a solvent that dissolves the powder. The purpose of the two-vial packaging is to keep the active ingredient fresh for as long as possible.

Only one or two drops of Vialox, smoothed into the face, are needed to address crow’s-feet, wrinkles on the forehead, frown lines, and nasolabial folds. Results can be seen within a month. The product lasts up to two weeks after mixing. Apply Vialox twice daily for the first month, and then maintain the positive effects with a daily application thereafter. A 14-day supply of Relax Plus Vialox sells for about forty-two dollars.


Revinage is made from a retinoid-like vegetable source that offers extra benefits for the skin. Retinoids are used as skin plumpers as they smooth and reduce wrinkles from inside the skin. They help stimulate collagen production and rejuvenate the skin, adding renewed elasticity.

Natural retinoids are derived from vitamin A, a substance contained in plant materials. They work to unclog pores, increase collagen production, and erase fine lines within just a few weeks’ time. Synthetic retinoids are very similar to natural retinoids. They activate retinoic acid receptors (RARs) in the skin. This helps trigger plumping, wrinkle smoothing, and lightening of the skin.

However, retinoids can sometimes be irritating to the skin. Revinage is formulated to eliminate this type of reaction by targeting only the RARs that are necessary to produce the desired effect. Most synthetic retinoids can be used in direct sunlight, while true retinoids cannot. While using a retinoid, such as Retin-A, you must apply a sunscreen to avoid sunburn or skin damage. (You may want to wear sunscreen even with synthetic retinoids just to ensure that there is no toxicity and that the retinoids remain stable in the sunlight).

Revinage decreases wrinkles and lightens the skin by reducing melanin production. It can also control oil production, resulting in fewer acne breakouts. Revinage also acts as an anti-inflammatory agent with anti-oxidant effects.


PhytoCellTec is a technology developed by Mibelle Biochemistry that protects skin stem cells. It is derived from the stem cells of a Swiss apple tree, which produces apples famous for their longevity which are rich in phytonutrients and suffer little shriveling over time. The plant’s stem cells are obtained using PhytoCellTec’s technology and placed into cosmetic skincare products to guarantee that skin cells live longer with less wrinkling. This technology helps protect human skin cells, slowing the aging process and minimizing wrinkling of the skin. The skin creams made with PhytoCellTec are enhanced through the addition of vitamins C and E.

The actual PhytoCellTec process intentionally damages a tiny piece of the plant material in order to induce calluses. These calluses are incubated on slide plates and, when developed, are harvested in order to obtain stem cells. These stem cells are then processed, captured, and placed into liposomes.

Melanostatin 5

Melanostatin 5 (or nonoapeptide-1) is a synthesized peptide used in cosmetic products to rid the skin of abnormal pigmentation, reduce wrinkles, and smooth the skin’s surface.

Peptides are strings of amino acids, the building blocks of life. When applied to the skin in the form of creams or lotions, synthesized peptides act as messengers to skin cell receptors, telling them how to react.

Melanostatin 5 is a synthesized peptide that works by stopping the melanocyte hormone that is stimulated by UV light. Melanostatin 5 instructs the melanocytes to stop producing melanin. This can lighten the skin’s pigmentation or prevent hyper-pigmentation. When included in anti-aging products, Melanostatin 5 can also help lighten dark circles under the eyes. The ingredient delivers very positive effects within four to twelve weeks when used in cosmetic creams and lotions. It lightens the skin by at least 33% with the initial application. Over time, and with continued use, that percentage increases.

This is a safe lightening ingredient that is quite effective and reliable. Products containing Melanostatin 5 do take time to work, but once they have taken effect, the results are usually very good. However, it is not a permanent solution to hyper-pigmentation. If a client stops using the cream or lotion, the product ceases to work and results fade.

Products should contain a high percentage of Melanostatin 5 in order to guarantee positive results. A minimum of 2-4% of the cream is the norm. Complimentary ingredients should also be present for the best outcomes. Ingredients such as (5%) Matrixl, (10%) Argireline, (3%) Rigin, (3%) Eyeliss and (5%) Regu-age are excellent additions. When you read the product label, look for higher percentages of each substance to achieve the best results.

With the addition of Melanostatin 5, skincare products lighten age spots, freckles, and melasma. They work in anti-aging creams to help brighten skin damaged by the sun, even out blotchiness, and firm the skin at the cellular level.

Matrixyl 3000

Matrixyl 3000, developed by the Sederma Corporation, is made up of two matrikines peptides, Pal-GHK (palmitoyl oligopeptide) and Pal-GQPR (palmitoyl tetrapeptide-7). These work together as antioxidants to fight the damaging effects of aging on the skin. Together they stimulate the matrix molecules (collagens and fibronectin) and enable Matrixyl 3000 to reduce wrinkles. Matrixyl 3000 is a white gel with a pH between 4.0 and 6.0, and a water content of 30%.

Pal-GHK is a short chain of three amino acids that are connected to palmitic acid, a fatty acid that improves the chain’s oil solubility and skin penetration. It is a collagen molecule that detects any decline in the skin matrix. GHK stimulates new collagen synthesis.

The other component of Matrixyl 3000, Pal-GQPR, is a short chain of four amino acids that is also connected to palmitic acid and works similarly to the Pal-GHK above. It also reduces interleukin-6 production, keratinocytes, and fibroblasts. This substance won’t promote inflammation or degrading of the skin matrix, either of which can lead to wrinkles and sagging. Pal-GQPR may help slow the decline of the skin matrix and stimulate the growth of new cells.

The addition of Matrixyl 3000 to cosmetic skincare products reduces wrinkles and improves the skin’s elasticity and tone. As an anti-wrinkle ingredient, Matrixyl reduces the density and volume of wrinkles and minimizes sagging of the neck and facial skin. Studies have shown that Matrixyl 3000 reduces wrinkle density by 33%, lessens wrinkle volume by 23%, and decreases wrinkle depth by 20%.

Matrixyl 3000 helps rejuvenate the skin’s dermal area, thereby fighting wrinkles. This ingredient helps stimulate collagen production, which in turn helps to produce a more even and luminous skin tone while increasing the thickness of the skin’s outer layer. The creams formulated with Matrixyl 3000 penetrate deeply into the skin where they can retain the moisture the skin needs.

This ingredient also aids in fighting free radicals, in evening skin tones, increasing skin’s thickness, keeping moisture in and making the skin feel firmer and healthier. In addition to Matrixyl 3000, some cosmetic skin products include other antioxidants such as copper peptides, marine collagen, grape, tea, and/or algae.


Argireline is an ingredient used in some anti-wrinkle cosmetic products. These products are applied directly to the skin. Argireline is actually the trademark name for acetyl hexapeptide-3, a molecule that is part of a peptide chain. Argireline is made up of a chain of six amino acids or proteins and so is shorter than a Botox string.

Argireline helps erase deep creases, wrinkles, and lines around the forehead and the eyes, like those found in crow’s-feet. When Argireline is added to a chemically-made cosmetic compound, it relaxes the muscles that cause the face to smile, frown, or make other expressions. Its function is very similar to that of Botox. By relaxing tension on the face, lines and wrinkles are much less likely to form in the first place. Neurotransmitters in the brain tell our facial muscles to tense in certain situations; Argireline inhibits these neurotransmitters, allowing the muscles to relax. When this ingredient is combined with other cosmetic components, it makes a wonderful, moisturizing, anti-aging, skin-resurfacing product.

Clinical experiments have shown that creams containing 10% Argireline reduced the depth of wrinkles in 27% of the women tested. Even with lower concentrations of the ingredient (5%), women still saw a 17% reduction in lines and creases.

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